Mesothelioma FAQ (Gene Therapy, Immunotherapy, VATS)

How does gene therapy work?

Gene therapy is a procedure for treatment of mesothelioma cancers by altering the expression of a person's genes in line a therapeutic goal. The objective and aim of gene therapy is centred on rectifying disease at DNA level and to compensate for the abnormal genes.

With Mesothelioma

How does replacement gene therapy work?

Mesothelioma FAQ (Gene Therapy, Immunotherapy, VATS)

Replacement gene therapy displaces a mutated gene, most often a tumor suppressor gene, and replaces it with a normal copy of that gene which function to control cell growth and division. The p53 gene, the most known and common gene altered in cancer has turned out to be a prime target for replacement of gene, and has been successful in preventing cell growth, preventing angiogenesis that is the development of a tumor's blood supply, and to induce apoptosis.

How does knockout gene therapy work?

Knockout gene therapy aims at the products of oncogenes (a gene that can stimulate the formation of tumour) with effort to rendering them inert and decrease the growth of cell.

How does immunotherapy work?

Immunotherapy, often times referred to as biological therapy is a new procedure for the treatment of mesothelioma cancers, which applies the use the body's own immune system to fight against disease in mesothelioma patients. Medical Researchers have discovered that the body's immune system is able to identify the difference between healthy cells and mesothelioma cancers, and destroy the bad or cancerous cells.

Immunotherapy as a treatment of mesothelioma is intended to repair, incite, or improve the body's immune system's innate anticancer role.

What is VATS?

Lately, the use of video-assisted thoracic surgery (VATS) have turned out to be one of the most commonly used techniques in mesothelioma diagnosis. Here, mesothelioma patients are usually put under general anesthesia, and then several small ports are cut through the wall of the chest,in the case of pleural mesothelioma. Then a small camera, through a scope is inserted into one of the incision, and tissues specimens or samples are retrieved from other openings using other surgical instruments.

In several cases, thoracotomy can be replaced by this video-assisted technique, which needs a much bigger port to get access to the chest cavity, and because of its minimal invasion, mesothelioma patients usually have less pain after the procedure and a short time to recover. Thoracotomy has been used in peritoneal mesothelioma.

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Treating Mesothelioma Alternative Treatments - TENS Therapy

Transcutaneous Electrical Nerve Stimulation, or TENS, is an effective method of pain relief that involves no drug interactions, is non-addictive and non-invasive, and has no harmful side effects. It can be used to give palliative treatment to those with the asbestos cancer mesothelioma. TENS can also be employed with other traditional means of treatment to reduce the effects of the cancerous cells.



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Living With Mesothelioma

Coping with mesothelioma

You may already know this sad fact: There is no early diagnosis for this disease and is usually found out at the advanced stage. You might find it very difficult to deal with the situation as you might be aware that there is no treatment for your disease and you have very little time left.

Along with coping with the fear and anxiety of the cancer you also need to work out strategies to manage your disease practically like arranging for money, dealing with family emotions, fighting a legal battle.

You need to choose the best mode of treatment for your disease depending on what stage it is which will give you maximum relief.

You need to gather maximum information about your disease and physiotherapists, specialist nurses and social workers who can all help you manage at home, as well as in hospital. You can discuss with various support groups located across the country with which you can discuss your fears and apprehensions.

Living with advanced cancer

Treatment can bring certain amount of respite to your disease. You can also get relief if you talk to others about your feelings. You should spend time with yourself to come to terms with the problem. There is no right or wrong solution to deal with the problem.

You should try all possible ways to live with the mesothelioma. You should come to terms with the fact that there is no cure to your advanced mesothelioma. It doesn't mean that you are going to die immediately. You should look for treatments which can slow down the complications of the cancer as well as reduce your pain.

You need advice from an expert in the field of mesothelioma to get information on the following:

" The diagnosis

" Treatment available

" How treatment can benefit you

It is found that people diagnosed with mesothelioma learn to live with the disease by appreciating everything around them, getting their priorities right, cherishing relationships and completing things that you always wanted to do.

A few questions that you can ask your physician about living with mesothelioma are:

" Time frame of my treatment

" Precautions that needs to be taken during the course of the treatment

" Kind of help available

" What kind of work can be done and what sports and hobbies can be pursued?

" Kind of travel that can be done

" Diet to be followed

" Cost involved for the treatment

" Claiming for compensation

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